ISSN 1306-0015 | E-ISSN 1308-6278
Original Article
Comparison of patients with familial mediterranean fever and juvenile ıdiopathic arthritis according to family origin
1 İstanbul Üniversitesi, Cerrahpaşa Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Çocuk Romatoloji Bilim Dalı, İstanbul, Türkiye  
2 İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Çocuk Romatoloji Bilim Dalı, İstanbul, Türkiye  
Turk Pediatri Ars ; : -
DOI: 10.5152/TurkPediatriArs.2017.5818
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Key Words: Familial Mediterranean fever, juvenile idiopathic arthritis, family origin, geographic regions of Turkey
Abstract

Introduction: Familial Mediterranean fever is an inherited condition that is more prevalent in some regions of Turkey. Juvenile idiopathic arthritis is the most common chronic arthritis of childhood. There is lack of studies on the frequency of these conditions across different regions of Turkey. We aimed to compare patients with familial Mediterranean fever and juvenile idiopathic arthritis according to their family origin.

 

Material and Methods: Patients with familial Mediterranean fever and juvenile idiopathic arthritis who were followed up at the department of pediatric rheumatology were assessed. Data on the family origin of patients were noted from their medical records. Both groups were compared according to their origins.

 

Results: A total of 704 patients with familial Mediterranean fever, and 204 patients with juvenile idiopathic arthritis were enrolled. The mean ages of the patients at the time of the study was 12.3 ± 4.4 years and 12.1±4.8 years, respectively. The frequency of familial Mediterranean fever was significantly higher among subjects with Black Sea and Central Anatolian origins (z score 2.69 and 3.69, respectively), particularly Kastamonu, Tokat and Sivas provinces. Juvenile idiopathic arthritis was significantly more common among subjects from the Marmara and Southeastern Anatolia regions (z score -4.11 and -2.54, respectively).

 

Conclusion: Familial Mediterranean fever is more common among subjects from the Black Sea and central Anatolia regions of Turkey, especially Kastamonu, Sivas, and Tokat provinces. Patients with juvenile idiopathic arthritis more commonly originate from Marmara and Southeastern Anatolian regions of Turkey.

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