ISSN 1306-0015 | E-ISSN 1308-6278
Case Report
Variant Guillain-Barré syndrome in a patient with Hodgkin Lymphoma: AMSAN
1 Department of Pediatric Hematology and Oncology, Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey.  
2 Department of Pediatric Hematology and Oncology, Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey.  
3 Division of Pediatric Neurology, Department of Pediatrics, İstanbul University School of Medicine, İstanbul, Turkey  
Turk Pediatri Ars ; : -
DOI: 10.5152/TurkPediatriArs.2018.4763
Key Words: Hodgkin Lymphoma; Guillain-Barré Syndrome; paraneoplastic syndrome
Abstract

 

Lymphomas are the solid tumors characterised by the malign proliferation of lymphoid cells. Neurological signs encountered in patients with Hodgkin Lymphoma (HL) can be due to direct spread of the tumor to the nervous system, secondary to chemotherapy or radiation, secondary to tumor mass compression, infectious causes,and paraneoplastic syndromes. Paraneoplastic neurological syndromes (PNSs) are rarely encountered in patients with HL and non-HLs (NHLs). Except for paraneoplastic cerebellar degeneration in HL and dermato/ polymyositis in both HL and NHL, other PNSs are uncommon and have only been reported as isolated case reports or short series. Here we present a case with HL with the complaint of bilateral lower extremity weakness and loss of sensation before start of the therapy, and eventually diagnosed with motor and sensory axonal neuropathy (AMSAN).

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